The 7 Best Nootropics(Smart Drugs) in the market of Sunifiram

以下博客转自：
https://www.aasraw.com/best-nootropics-in-the-market-of-sunifiram/

Sunifiram ( DM-235 ) is an experimental drug that acts as a positive allosteric modulator of the AMPA receptor, 1 which has been shown to have nootropic effects in animals with a significantly higher potency than that of piracetam. A series of related compounds are known, one being the unifiram (DM-232).

1. Sunifiram powder 314728-85-3 Chemical properties

CAS Number: 314728-85-3
Formula C14H18N2O2
Molar mass 246.304 g/mol

2. Sunifiram (314728-85-3) is a nootrop or a drug.

Nootropic drugs gradually, but surely, are part of our life-filled, stressful life. Today they are represented in a wide variety, with many being at the stage of development and research, while others are unknown.
Nootropic drugs gradually, but surely, are part of our life-filled, stressful life. Today they are represented in a wide variety, with many being at the stage of development and research, while others are unknown. The black market is full of nootropics, because the demand for them is growing – people have always wanted to use the reserves of the brain to the maximum.
Many drugs of this group can not be imported into Russia and sold. But the forbidden does not mean bad. A vivid example of such a tool is Sunfiram (prohibited for importation). According to official information, he has not yet passed sufficient number of necessary tests on people. Nevertheless, the results of scientific research available at the moment allow us to draw conclusions about its high efficiency.

Many people have already experienced the effect of Sunifiram. Some have completely solved health problems. Judging by the experimental data and conclusions of the scientists, the drug does not cause side effects, so even if it is not possible to eliminate the disease, then, at least, it will be possible to stop its development without harming the body. In this article I would like to reveal the peculiarities of using Sunfire on the basis of information received at the forums, and talk about the possibility and impossibility of its purchase on the Russian market.

3. Sunifiram (dm 235) – what kind of nootropic, what is its principle of action, dosages, reviews

Sunfyram (chemical formula C14H18N2O2) is a derivative of a pyracetam compound synthesized. It has the same effect as the rest of the racetamen, but is more powerful and less toxic than the precursor. The main course of action of dm-235 is the activation of AMPA receptors, which ensure the production of the neurotransmitter glutamate, in connection with which it is classified as ampakines.
Glutamate plays a key role in the state of the cognitive sphere, its deficiency leads to memory loss, learning difficulties, inability to concentrate, etc. In animal studies, it has been shown that even with the artificial blocking of AMPA receptors, sunifirum stimulates sufficient production of glutamate in the central nervous system.
In addition, like the rest of the ratsetam, Sunifiram increases the activity of cholinergic receptors. As a result, the effect of the drug leads to such effects as:
• facilitates memorization;
• supports the structure of the central nervous system during periods of increased mental stress;
• improves the transmission of impulses between neurons;
• controls the vital activity of brain cells;
• normalizes and enhances metabolism in the brain;
• increases attention, concentration, exacerbates vigilance and perception;
• contributes to improving the relationship between the hemispheres and so on.
Approved instructions for the application of Sunifiram no. The drug is administered in a single dose of 10-50 mg. In practice, the working dose of dm-235 is at least 30 mg sublingually. In general, it is necessary to take into account that the experience of applying nootropics is rather small, in comparison with foreign users. Therefore, it is necessary to listen with care to the majority of “councils”.

4. Sunifiram powder Dosage

The appropriate oral dose of Sunifiram needed may vary depending on the conditions of use, for cognitive impairment it is 2.4-4.8g daily.

5. What effect does Sunifiram have?

drugs have an effect in that they trigger a change in the transmission of messenger substances and form nerve cells from certain stem cells. The different preparations prove their effectiveness on the central nervous system by causing positive changes in the brain. They increase concentration and memory and increase motivation and mood. This is why Sunifiram have long been known in Germany and are used for various purposes, including anti-aging and wellness. Sunifiram are legal and can be purchased in pharmacies or from appropriate online providers.

Since the specific effect of individual preparations differs from others, the appropriate agent should be selected before the start of treatment. While some products encourage creativity, other supplements increase intelligence. With the right Sunifiram drug you can achieve specific effects and, depending on your individual needs, provide more motivation and concentration, or build up a higher resistance to stress and counteract memory deficiency.

6. Where and in what form is it used Sunifiram?

The drugs are mainly offered in capsule form for oral use and are almost without side effects, as the ingredients are virtually non-toxic. A Sunifiram list makes it easy to find the right preparation for each therapy.

7. What are the side effects of Sunifiram?

If taken prescriptively, you do not have to expect side effects. However, over time, the body builds tolerance to the drug. After prolonged ingestion gradually diminishes the effect. Therefore, treatment should not take longer than recommended in the package leaflet. At higher doses, the agents have a stimulating effect, which may cause mild palpitations or discomfort.

8. Which Sunifiram experience is known?

Most users reported a reliable effect of the preparations and described their Sunifiram experience as good. With the substance, learning ability and memory can be improved in everyday life. In addition, the preparations have a positive influence in coping with stressful situations. They protect the brain from physical and psychological attacks caused by drugs or barbiturates.
The preparations themselves have no stimulating and anesthetic effects. Therefore, most users used the products in their daily lives without any consequences. In pharmacology, the agents are also referred to as neuro-enhancers or smartpills used to maintain and enhance intellectual performance. However, the products are mainly used as a therapy for diseases that reduce the brain activity. In these areas, the mode of action has been proven for a long time and users report invariably good results.
In the meantime, more and more healthy people are also resorting to the means to better master work and everyday life through a higher mental capacity. Using a Sunifiram powder list, every consumer will find the preparation that best suits their purpose. A secure effect possesses the substance with regard to the increase in concentration. For this reason, many consumers claimed to use the product as a “brain doping” in high stress during study or at work. The medicines, in addition to better coping with stressful situations, have other health aspects as well. They increase creativity and help with difficult decisions and reduce premature actions. In addition, sleep patterns change, contributing to improved recovery.

Oxandrolone Powder CAS 53-39-4

I.Oxandrolone powder (Anavar powder) basic Characters:

Name:	Oxandrolone powder(Anavar powder)
CAS:	53-39-4
Molecular Formula:	C19H30O3
Molecular Weight:	306.4397
Melt Point:	235-238℃
Storage Temp:	RT
Color:	White or off white crystalline powder

II.Oxandrolone powder((Anavar powder) usage in steroids cycle

1. Names:

Oxandrolone powder is well know as it’s brand name Anavar powder.

2.Oxandrolone powder Usage:

5-10mg per day range with 20mg per day normally being the maximum dose. Such use will normally last 2-4weeks with a small break after use before implementing the next 2-4 week cycle.
For the male performance enhancing athlete, 1 20-30mg per day dosing will provide athletic enhancement, but most will find 40-50mg per day to be far more efficient. 80mg per day is not uncommon, but this will increase the risk of side effects.

3. Warning on Anavar powder:

Side effects are certainly possible, but for the healthy adult they can be minimized. Unlike another popular dihydrotestosterone derived anabolic steroid in Anadrol, Anavar is what we’d call a rather side effect friendly anabolic steroid.

4.Further instructions:

Oxandrolone powder takes the leading positions from the very beginning of its existence.The major ingredient of Anavar powder is called Oxandrolone powder. Its main advantage is the capability of substituting carbon atom by oxygen. The amazing results at the gym are reached thanks to a small androgenic index and the increased anabolic capabilities.

5.Raw Oxandrolone(Anavar) powder:

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.

6. Oxandrolone Powder Recipes:

To inquiry our Customer Representitive(CSR) for details, for your reference.

7. Oxandrolone powder Marketing:

To be provided in the coming future.

 III.Oxandrolone(Anavar) powder HNMR

Sunifiram ( DM-235 ) is an experimental drug that acts as a positive allosteric modulator of the AMPA receptor, 1 which has been shown to have nootropic effects in animals with a significantly higher potency than that of piracetam. A series of related compounds are known, one being the unifiram (DM-232).

1. Sunifiram powder 314728-85-3 Chemical properties

CAS Number: 314728-85-3
Formula C14H18N2O2
Molar mass 246.304 g/mol

2. Sunifiram (314728-85-3) is a nootrop or a drug.

Nootropic drugs gradually, but surely, are part of our life-filled, stressful life Today they are represented in a wide variety, with many being at the stage of development and research, while others are unknown.
Nootropic drugs gradually, but surely, are part of our life-filled, stressful life. Today they are represented in a wide variety, with many being at the stage of development and research, while others are unknown. The black market is full of nootropics, because the demand for them is growing – people have always wanted to use the reserves of the brain to the maximum.
Many drugs of this group can not be imported into Russia and sold. But the forbidden does not mean bad. A vivid example of such a tool is Sunfiram (prohibited for importation). According to official information, he has not yet passed sufficient number of necessary tests on people. Nevertheless, the results of scientific research available at the moment allow us to draw conclusions about its high efficiency.

Many people have already experienced the effect of Sunifiram. Some have completely solved health problems. Judging by the experimental data and conclusions of the scientists, the drug does not cause side effects, so even if it is not possible to eliminate the disease, then, at least, it will be possible to stop its development without harming the body. In this article I would like to reveal the peculiarities of using Sunfire on the basis of information received at the forums, and talk about the possibility and impossibility of its purchase on the Russian market.

3. Sunifiram (dm 235) – what kind of nootropic, what is its principle of action, dosages, reviews

Sunfyram (chemical formula C14H18N2O2) is a derivative of a pyracetam compound synthesized. It has the same effect as the rest of the racetamen, but is more powerful and less toxic than the precursor. The main course of action of dm-235 is the activation of AMPA receptors, which ensure the production of the neurotransmitter glutamate, in connection with which it is classified as ampakines.
Glutamate plays a key role in the state of the cognitive sphere, its deficiency leads to memory loss, learning difficulties, inability to concentrate, etc. In animal studies, it has been shown that even with the artificial blocking of AMPA receptors, sunifirum stimulates sufficient production of glutamate in the central nervous system.
In addition, like the rest of the ratsetam, Sunifiram increases the activity of cholinergic receptors. As a result, the effect of the drug leads to such effects as:
• facilitates memorization;
• supports the structure of the central nervous system during periods of increased mental stress;
• improves the transmission of impulses between neurons;
• controls the vital activity of brain cells;
• normalizes and enhances metabolism in the brain;
• increases attention, concentration, exacerbates vigilance and perception;
• contributes to improving the relationship between the hemispheres and so on.
Approved instructions for the application of Sunifiram no. The drug is administered in a single dose of 10-50 mg. In practice, the working dose of dm-235 is at least 30 mg sublingually. In general, it is necessary to take into account that the experience of applying nootropics is rather small, in comparison with foreign users. Therefore, it is necessary to listen with care to the majority of “councils”.

4. Sunifiram powder Dosage

The appropriate oral dose of Sunifiram needed may vary depending on the conditions of use, for cognitive impairment it is 2.4-4.8g daily.

5. What effect does Sunifiram have?

drugs have an effect in that they trigger a change in the transmission of messenger substances and form nerve cells from certain stem cells. The different preparations prove their effectiveness on the central nervous system by causing positive changes in the brain. They increase concentration and memory and increase motivation and mood. This is why Sunifiram have long been known in Germany and are used for various purposes, including anti-aging and wellness. Sunifiram are legal and can be purchased in pharmacies or from appropriate online providers.

Since the specific effect of individual preparations differs from others, the appropriate agent should be selected before the start of treatment. While some products encourage creativity, other supplements increase intelligence. With the right Sunifiram drug you can achieve specific effects and, depending on your individual needs, provide more motivation and concentration, or build up a higher resistance to stress and counteract memory deficiency.

6. Where and in what form is it used Sunifiram?

The drugs are mainly offered in capsule form for oral use and are almost without side effects, as the ingredients are virtually non-toxic. A Sunifiram list makes it easy to find the right preparation for each therapy.

7. What are the side effects of Sunifiram?

If taken prescriptively, you do not have to expect side effects. However, over time, the body builds tolerance to the drug. After prolonged ingestion gradually diminishes the effect. Therefore, treatment should not take longer than recommended in the package leaflet. At higher doses, the agents have a stimulating effect, which may cause mild palpitations or discomfort.

8. Which Sunifiram experience is known?

Most users reported a reliable effect of the preparations and described their Sunifiram experience as good. With the substance, learning ability and memory can be improved in everyday life. In addition, the preparations have a positive influence in coping with stressful situations. They protect the brain from physical and psychological attacks caused by drugs or barbiturates.
The preparations themselves have no stimulating and anesthetic effects. Therefore, most users used the products in their daily lives without any consequences. In pharmacology, the agents are also referred to as neuro-enhancers or smartpills used to maintain and enhance intellectual performance. However, the products are mainly used as a therapy for diseases that reduce the brain activity. In these areas, the mode of action has been proven for a long time and users report invariably good results.
In the meantime, more and more healthy people are also resorting to the means to better master work and everyday life through a higher mental capacity. Using a Sunifiram powder list, every consumer will find the preparation that best suits their purpose. A secure effect possesses the substance with regard to the increase in concentration. For this reason, many consumers claimed to use the product as a “brain doping” in high stress during study or at work. The medicines, in addition to better coping with stressful situations, have other health aspects as well. They increase creativity and help with difficult decisions and reduce premature actions. In addition, sleep patterns change, contributing to improved recovery.

The 8 Most Influential Sex Drug Powder In The World

A loss of libido, in both women and men, is a common problem, usually due to fatigue, stress, age or simply routine. To arouse desire, there are sex drugs that are used to boost this.
In 1998, the Food and Drug Administration of the United States and Europe ( FDA and EFSA) approved the ED for the market treatment of Viagra(Sildenafil citrate 171599-83-0), which caused a sensation worldwide. The clinical results of sildenafil citrate 171599-83-0 are published in the top medical journal New England Journal of Medicine.

Sex drug classification

Those used by Male

-Tadalafil (Cialis) CAS 171596-29-5
Tadalafil 171596-29-5, is used in treatment of erectile dysfunction. The tadalafil is a drug inhibiting the enzyme phosphodiesterase type 5 (PDE-5) responsible for disabling the vasodilator nitric oxide, currently marketed as tablets under the trade name Cialis. It has also been recently approved for the treatment of pulmonary arterial hypertension, and has been used for other conditions. The tablets of Cialis , of 5mg, 10mg and 20mg of dose, are of yellow color covered with a film and in the form of almond. The approved dose for pulmonary hypertension is 20 mg and is marketed under the brand Adcirca.
Clinical studies have shown that tadalafil can enhance the antihypertensive effect of nitrate drugs. This is believed to be the result of a combination of nitrates and tadalafil on the nitric oxide/cGMP pathway. Therefore, patients taking any form of nitrates are prohibited from taking this product.

-Sildenafil Citrate(Viagra) CAS 171599-83-0
Sildenafil citrate 171599-83-0  is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PPH). Sildenafil can selectively inhibit PDE5 activity in humans. PDE5 is highly expressed in the penis sponge and low in other tissues and organs. After taking sildenafil, the corpus cavernosum vasomotor muscle relaxes under the action of the drug, the blood flow is increased, the cavernous body is congested, and the penis is erected, thereby producing a therapeutic effect on penile erectile dysfunction.
Patients with penile erectile dysfunction have an average duration of action of 27 minutes after oral administration (clinical data are distributed between 12 and 70 minutes).

-Vardenafil HCL(Levitra) CAS 224785-91-5 
Vardenafil 224785-91-5 is used to treat penile erectile dysfunction. This drug is a type 5 phosphodiesterase (PDE5) inhibitor. Oral administration of this drug can effectively improve the quality and duration of erection and improve the sexual success rate of male patients with erectile dysfunction. The initiation and maintenance of penile erection is related to the relaxation of cavernous smooth muscle cells.
In addition to being used to treat erectile dysfunction, vardenafil can also prevent premature ejaculation.

-Avanafil(Stendra) CAS 330784-47-9
Avanafil 330784-47-9 is a prescription drug from the group of PDE-5 inhibitors used in the treatment of erectile dysfunction. Vardenafil has been clinically proven to be a new generation of phosphodiesterase 5 (PDE5) inhibitor, and vardenafil hydrochloride is highly potent, highly selective, and well tolerated. Its advent has brought new options for the treatment of erectile dysfunction (ED).
The effects of PDE-5 inhibitors require sexual arousal. Depending on individual efficacy and tolerability, the dose may be increased to a maximum of 200 mg or reduced to 50 mg. Compared to other PDE-5 inhibitors, a higher selectivity of avanafil for phosphodiesterase-5 (PDE-5) was shown, resulting in better tolerability.

-Udenafil (Zydena) CAS 268203-93-6
Zydena (Udenafil 268203-93-6) was developed in South Korea (by Dong-A Pharm), launched in 2005. Udenafil is a PDE-5 inhibitor. Zydena is considered a safe drug for erectile dysfunction without serious side effects such as blurred vision, no serious side effects have been found so far. But that is a short time in the international market, there are not so many studies. 30 minutes are necessary for the remedy to take effect. The ingestion, the dosage form, contraindications, the mode of action are equal to Viagra.

Female use 

- Flibanserin HCL(Addyi) CAS 147359-76-0
Flibanserin 147359-76-0  is a drug originally developed for the treatment of depression, but has been found to be ineffective in this area and has now been re-approved for the treatment of hypoactive sexual dysfunction (HSDD) in women - however, efficacy is not confirmed here has led to many controversies around the topic of flibanserin (Addyi) and its alleged effect.
In the clinical trials conducted, it has been proven that the substance improves between 0.5 and 1 the number of successful sexual experiences in the period of one month, comparing it with a placebo, a modest but statistically significant efficacy. The women who participated in the study started it with an average of between 2 and 3 satisfactory monthly sexual experiences.
Flibanserin HCL Mechanism of action, it acts on neurotransmitter pathways, both excitatory and inhibitory. Through an agonist action on the 5-HT 1A receptors of serotonin , a mechanism similar to that of various antidepressant drugs and through an antagonistic action of 5-HT 2A receptors.

Time Delay: 
- Dapoxetine HCL CAS 119356-77-3 
The dapoxetine HCL 119356-77-3 is a drug used for the treatment of premature ejaculation. It is a selective serotonin reuptake inhibitor of short duration and action. On the basis of the previous study situation, a three- to four-fold prolongation of the intravaginal latency period of ejaculation can be assumed. In addition, dapoxetine can improve sexual satisfaction and perceived control over male ejaculation, and reduce the suffering and interpersonal difficulties.

- Dyclonine HCL CAS 536-43-6
Dyclonin HCL 536-43-6 is a topical anesthetic that can be used for anesthesia of mucous membranes before medical examinations and procedures. It is also found in lozenges and sprays for the throat and throat area. Dyclonin can also be used to suppress the gag reflex.
This product can block the transmission of various nerve impulses or stimuli, inhibit the sense of touch and pain, and have analgesic, antipruritic and bactericidal effects on the skin.
This product is an aromatic ketone type local anesthetic. It has a fast onset and lasts for a long time. It has antipruritic, analgesic and bactericidal effects on the skin.

Conclusion and recommendation

Reasons to take a sex drug
A sex drug can help you solve some problems. However, if after taking a stimulant for a while, your problem is still not resolved, do not hesitate to consult a professional (sexologist or doctor) to expose your problem. The latter will give you advice and solutions to fight it.

Here are the different detailed goals of a sex drug.

-Help to regain some pleasure during your sexual intercourse
Here is the main purpose of a sex drug: to help people to have fun while having sex with their spouse. For this, it is of course important to take into account the dosage indicated on the product box, but if you respect it, your libido can only be boosted and the desire for your reports can only be found.

-To fight blockages and fight against erection problems
If you face an erection problem , a sex drug can help you fight it. In addition to fighting against this disorder, you will also find a fulfilling sexuality and you can satisfy your spouse without being afraid of a "breakdown" during the act; a frustrating and embarrassing feeling at a time.
Women are not immune to a blockage either . Again, to combat this problem, taking a sex drug can be interesting. With this last ladies, your blockages will disappear and you will feel more fulfilled when acting out.

-To improve your sexuality and your relationships
Do you want to have intense sex? Do you dream of finding pleasure during your actions? A sex drug can help you regain those feelings! This product can be taken by men as well as by women wishing to live an intense sexuality and wishing that their relations happen in the best possible conditions.
Taking a sex drug will therefore be of great help and thanks to him, your intimate relationships will be more than perfect!

-To boost your libido
During life, there may be times when a man or woman no longer wishes to have sex with their spouse. This problem is mostly psychological and can be due to different factors: fatigue, personal problems, stress ... These can cause a drop in libido and pleasure .
To regain these two feelings, taking a sex drug can be effective. Indeed, it can help you boost your libido and regain a certain sexual appetite!

And if you want some tips to prolong the pleasure, here is a useful article !

What is the best sex drug for men?

Currently, there are many sex stimulants for men on the market. Choosing and buying the best can be difficult and it is not uncommon to find oneself lost in the face of these multiple choices. In the rest of this article, I give you several effective sex drugs that will help you improve your libido for sure!
But before you discover them, know that the first thing to do is to talk to your doctor. This professional will tell you if taking a stimulant is necessary and if it is compatible with your general state of health. In any case, the majority of industrial sex stimulants such as Viagra or Vialis can only be given on medical prescription and it is therefore obligatory to consult your doctor if you wish to obtain them.
Also, the different products presented below are not aphrodisiacs . They are not there to increase your libido, but aim to increase blood flow directly into your penis to get and keep a proper erection during your sexual intercourse.
These stimulants will help you to have a satisfactory erection, but not without effort. For it to take place, sexual stimulation will have to be put in place.

8 Important Things Of Stenbolone Powder(5197-58-0)

8 Important Things Of Stenbolone Powder(5197-58-0)

Stenbolone powder(5197-58-0), brand name anatrofin, is an anabolic–androgenic steroid (AASraw) of the dihydrotestosterone (DHT) group. As Stenolone never marketed, so it is hard to find Stenolone today. Nevertheless, there is always the possibility of this compound regaining its popularity, especially if the appeal for the lean muscle mass look will return to bodybuilding again. 

1. Stenbolone history? 

Stenbolone powder(5197-58-0)is an injectable anabolic steroid that was developed in the 1960's in Germany.Stenbolone was introduced first in Germany by Schering, and two years later Syntex brought it to the United Kingdom, followed by Mexico, under the brand name Anatrofin. Eventually, it was brought to Spain under the Stenbolone name. Just like many anabolic androgenic steroids (AAS), anatrofin was used for its wonderful effects on anemia, and it was a very popular alternative to anadrol for this purpose because it had less side effects.

2. What is Stenbolone ? 

Stenbolone powder(5197-58-0)is very similar to both dromostanolone and oxymetholone. It is a derivative of DHT with a double bond between carbon 1 and 2 and a methyl group at position 2. The methyl group at position 2 protects the molecule from both aromatization to estrogen and to some degree, inactivation in muscle tissue by 3-alpha hydroxysteroid dehydrogenase. This 2-methyl group does decrease binding to the androgen receptor somewhat. This makes for a molecule that has slightly less binding affinity for the androgen receptor than primobolan but like primobolan, this steroid cannot be converted to estrogenic metabolites through aromatization. Stenbolone is considered by some to be a gentler version of oxymetholone. This steroid has a similar structure to oxymetholone but is not C-17 alpha alkylated so it has minimal effects on liver function. Stenbolone builds up red blood cells like oxymetholone and is metabolized to some degree to dromostanolone which has also been shown to increase red blood cells.

As a matter of fact, steroid guru Daniel Duchaine considered anatrofin as one of his favorite steroids, and has written that if he had to pick one compound to run for the rest of his life, he would choose Stenbolone. This shows how popular Stenbolone powder is in the fitness market.

3. Stenolone effects 

Stenbolone effects is neither liver-toxic nor does it aromatize, and it is only slightly an-drogenic. In addition, it has a similar effect to Anadrol in cases of anemia with abnormal blood formation since it increases the num-ber of red blood cells. For this reason Stenbolone is especially suit-able for competing athletes since it accelerates regeneration when dieting. Competing body builders in the weeks before a champi-onship often experience a catabolic phase and a condition of over training. Stenbolone rapidly and reliably counters this and helps to obtain a good form since it does not draw water and does not increase the estrogen level. For the buildup of strength and mass, however, Stenbolone results is by far not as suitable as Anadrol, although some erroneously call it an injectable Anadrol. Stenbolone results has lower anabolic and androgenic effects than the oral version and it leads to a slow but solid muscle gain along with a moderate strength gain. For this purpose it is preferred by women and ste-roid novices, and by older athletes who obtain satisfying results without the fear of significant side effects. Despite this, Stenbolone is, above all, I a competition steroid which is confirmed by the American Steroid Guru Daniel Duchaine in his book Underground Steroid Handbook 2: "This is an excellent steroid to use while diet-ing..."

Steroid Guru Daniel Duchaine is a controversial figure in the bodybuilding world, once described as a “cross between Andy Kaufman and Albert Einstein, with some Bart Simpson thrown in.” A recent release of Federal Bureau of Investigation records on Duchaine reveal him as not only an expert on masking the use of anabolic steroids in athletes, but also an expert at masking their trafficking from the FBI.

4. Stenolone half life

The common form of Stenbolone is Acetate type(stenolone acetate). As the reader can guess, with the acetate ester attached, the stenolone half life is only 3 days. This means that you will need to inject stenolone(anatrofin) much more often than the common ester of primobolan enanthate.

Remember, half life doesn't mean how long the compound stays in your system - it means the duration of time that will elapse, when half of the compound will be left. Having said this, with the acetate ester, either everyday or every other day injections are recommended.

5. PIP 

Stenbolone does not seem to result in as much size gain as anadrol or as much bloat so it likely does not have as much inhibitory activity on 11-beta hydroxylase. Stenbolone tended to be injected daily because of the short half-life of the acetate ester. Additionally, the stenolone acetate ester seems to produce pain and swelling at the injection site. Stenbolone has similar androgenic activity compared to 1-testosterone, the unmethylated version of this drug, but with higher anabolic activity. This is likely due to the reduced conversion to 3-alpha hydroxy metabolites. Stenbolone offers many of the advantages of oxymetholone with less bloating and elevated blood pressure.

PIP stands for post injection pain, which is a known problem to deal with when cycling anatrofin. The best way to combat this, is to mix the oil with another compound to dilute its bite. Furthermore, injecting small amounts per muscle each time can considerably help decrease the PIP. Unfortunately, this can become troublesome, since the dosage typically averages 500 milligrams (mg) per week for males. Thus, if you manage to get a hold of this stuff, expect to make a lot of painful injections

6. Stenbolone dosage 

Since the substance is in acetate form it has only a low half-life time so that frequent and regular injections are necessary in order to ob-tain sufficiently high and constant blood level values. For optimal results Stenbolone is normally taken daily and injected at least ev-ery 2 days. The usual weekly stenbolone dosage for athletes is 200-300 mg. For this reason the 50 mg strength is often preferred and the athlete either injects the entire one-milliliter ampule daily or limits the use to half of it. Women normally do well with stenbolone dosage 100- 150 mg/week and should divide their weekly dosage into three equal parts. The poten-tial side effects are low since the compound is well tolerated by the liver and edemas, gynecomastia, and high blood pressure do not occur. Cases of acne and increased aggressiveness in men are low and rare, as is a reduction in the body's own hormone production. Virilization symptoms in women also occur rarely and for the most part in very sensitive persons when high dosages are given or when the intake interval lasts over several weeks.

7. Stenbolone side effects 

The stenbolone side effects are automatically going to be low, as this compound does not aromatize into estrogen at all. Therefore, such estrogenic side effects as increased blood pressure, insomnia, water retention, and gyno will not occur. Interestingly enough, anatrofin does have slight androgenic traits, even without the aromatization of estrogen, leading to a possibility of having some acne, oily skin, and increased aggression. Thus, women should be wary of this steroid.

8. Stenbolone for sale

Stenbolone Chemical Description

Name	Stenbolone,Stenbolone Acetate
CAS	5197-58-0
Molecular Formula
Molecular Weight	302.45
Melt Point	154-156°C
Appearance	powder
Manufacturer	www.aasraw.com

 

 

 

 

 

 

 

 

 

 

 

 

Stenbolone powder is very popular in the bodybuilding market, unfortunately, this compound is very difficult to find today, and even though there were rumors of possibly only one company still producing it overseas, they were not confirmed. AASraw provide stenbolone for sale online, click here to get your stenbolone powder easy,fast and safely. 

 

 

 

 

Cyproterone Acetate Ethinylestradiol:Mechanism,Uses,Information Part2

Cyproterone Acetate Ethinylestradiol:Mechanism,Uses,Information Part2

 

1. What is Cyproterone Acetate Ethinylestradiol?    
2. Cyproterone Acetate Mechanism of Action    
3. Cyproterone Acetate half life    
4. What is the use of Cyproterone Acetate Enthinylestradiol?    
Cyproterone acetate uses- prevent these actions of the androgens:    
Cyproterone Acetate uses-Cyproterone Acetate birth control:    
Cyproterone Acetate uses-Treatment in Women with Acne    
5. Is cyproterone acetate a progesterone?    
6. What forms does Cyproterone Acetate come in?    
7. How should I take Cyproterone Acetate?    
8. What other information should I know before taking Cyproterone
Acetate?    
Other medicines, foods and drink    
Alcohol    
Treatment for other conditions    
If you have diabetes    
Contraception    
Fertility    
9. What are Cyproterone Acetate possible side effects?    
10. Cyproterone Acetate drug interaction    
 

 

1. What is Cyproterone Acetate Ethinylestradiol?

Cyproterone Acetate Ethinylestradiol, CAS No.427-51-0, belongs to a group of medications known as steroidal antiandrogens. It is used to treat advanced prostate cancer.Antiandrogens such as cyproterone block the effect of the hormone called testosterone. This causes a reduction in the production of testosterone in the testicles, which prostate cancer cells require for growth.

Cyproterone acetate may be available under multiple brand names and/or in several different forms. it is sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others. 

Cyproterone is an antiandrogen. It suppresses the actions of testosterone (and its metabolite dihydrotestosterone) on tissues. It acts by blocking androgen receptors which prevents androgens from binding to them and suppresses luteinizing hormone (which in turn reduces testosterone levels).

Cyproterone Acetate Chemical Information

Name	Cyproterone Acetate,Ethinylestradiol
CAS	427-51-0
Molecular Formula	C24H29ClO4
Structure
Molecular Weight	416.94
Melt Point	200-201°C
Storage Temp	2-8°C
Appearance	white powder
Factory	www.aasraw.com
Package	foil bag or customization

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2. Cyproterone Acetate Mechanism of Action

Cyproterone acetate is a hormonal therapy drug used to treat prostate cancer,hormonal therapies affect different people in different ways.What is Cyproterone Acetate mechanism of action? How does Cyproterone Acetate work?

The direct antiandrogenic effect of cyproterone actate is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In addition, cyproterone exerts a negative feed-back on the hypothalamo-pituitary axis, by inhibiting the secretion of luteinizing hormone resulting in diminished production of testicular testosterone.

Cyproterone acetate is metabolized by the CYP3A4 enzyme, forming the active metabolite 15beta-hydroxycyproterone acetate, which retains its antiandrogen activity, but has reduced progestational activity.

3. Cyproterone Acetate half life 

Cypropterone Acetate half life is not long. 

Elimination:

Following oral or intramuscular administration, the plasma half-life is 38 and 96 hours, respectively.

Time to peak concentration:

Peak plasma concentrations are reached three to four hours after oral administration. Following intramuscular administration, mean peak blood concentrations are attained 3.4 days after injection.

Elimination:

Biliary—
        60% in the form of glucuronidized metabolites within 72 hours.

Renal—
        33% mainly in the form of unconjugated metabolites within 72 hours.

4. What is the use of Cyproterone Acetate Enthinylestradiol?

Cyproterone acetate uses is a type of medicine called an anti-androgen. Androgens are male hormones and are produced by women as well as men. They are responsible for stimulating the growth of the skin, including the sebaceous glands that produce oil (sebum), and the hair that grows from the skin. However, if your body produces too much androgen, or if your skin is particularly sensitive to the effects of androgens, the sebaceous glands may produce too much sebum. This can cause the sebaceous glands to become blocked, resulting in infection, inflammation and acne spots. The androgens may also cause excessive growth of the hair on the face and body - a condition known as hirsutism. Both these problems are common in women with polycystic ovary syndrome (PCOS).

Cyproterone acetate uses- prevent these actions of the androgens: 

It works by blocking the receptors in the body that the androgens normally work on. This means that the androgens can no longer affect the skin or the hair and acne and hirsutism can improve. Cyproterone acetate also decreases the production of androgens by the ovaries, so that there are less of these male hormones circulating.

You should notice that your skin becomes less greasy within a few weeks of treatment with this medicine, but it may take a few months of treatment before you see a definite improvement in your acne or excessive hair growth.

Cyproterone Acetate uses-Cyproterone Acetate birth control: 

This medicine is also an effective combined oral contraceptive pill. Cyproterone acetate is a progestogen derivative, and the other ingredient, ethinylestradiol, is a synthetic version of the naturally-occurring female hormone, oestrogen. The medicine works as a contraceptive by preventing the ripening and release of eggs from the ovaries, as well as increasing the thickness of the cervical mucus, which makes it more difficult for sperm to cross from the vagina into the womb. It also changes the lining of the womb so that it is less suitable for any fertilised eggs to successfully implant in.

Cyproterone Acetate is as effective a contraceptive as any other combined pill, but it should not be used solely for this purpose. It is used to treat severe acne and hirsutism in women and has the advantage of also providing contraception(cyproterone acetate birth control). This means you do not need to use any other method of contraception while you are using this medicine(cyproterone acetate birth control), unless you miss a pill, have a stomach upset, or are prescribed certain other medicines as well. See below for more information about all of these scenarios.

Cyproterone Acetate uses-Treatment in Women with Acne

The therapeutic effect of topically applied cyproterone acetate for acne treatment was clearly demonstrated. Topically applied sexual steroids in combination with liposomes are as effective as oral antiandrogen medication in acne treatment, while reducing the risk of adverse effects and avoiding high serum cyproterone acetate concentrations.

HORMONAL approaches to the treatment of acne have been the subject of much interest ever since the sebaceous gland was demonstrated to be sensitive to androgens. The use of topical antiandrogens has had theoretical appeal since the pilosebaceous unit was found to be an androgen-dependent structure. 

5. Is cyproterone acetate a progesterone?

Cyproterone acetate is a 17-hydroxyprogesterone acetate derivative with strong progestagenic properties. Cyproterone acetate acts as an antiandrogen by competing with DHT and testosterone for binding to the androgen receptor. There is also some evidence that cyproterone acetate and ethinyl estradiol in combination can inhibit 5α-reductase activity in skin.Cyproterone acetate is not available in the United States but has been used in other countries. The drug usually is administered daily in cyproterone acetate doses of 50 to 100 mg on days 5 through 15 of the treatment cycle. Because of its slow metabolism, it is administered early in the treatment cycle; when ethinyl estradiol is added, it is usually administered in 50-µg doses on days 5 through 26. This regimen is needed for menstrual control and is usually referred to as the reverse sequential regimen. Cyproterone acetate doses of 50 to 100 mg/day, combined with ethinyl estradiol at 30 to 35 µg/day, is as effective as the combination of spironolactone (100 mg/day) and an oral contraceptive in the treatment of hirsutism. In smaller doses (2 mg), cyproterone acetate has been administered as an oral contraceptive in daily combination with 50 or 35 µg of ethinyl estradiol. This regimen is primarily suited for individuals with a milder form of hyperandrogenism.

6. What forms does Cyproterone Acetate come in? 

Each cyproterone acetate tablets off-white, round, flat-faced, bevelled-edged tablet, embossed "CYP" over "50" and scored on one side, contains cyproterone acetate 50 mg. Nonmedicinal ingredients: colloidal silicon dioxide, croscaramellose sodium, and magnesium stearate.

7. How should I take Cyproterone Acetate? 

Cyproterone Acetate(Ethinylestradiol)is available as an oral (by mouth) tablet and as a long-acting injectable. The recommended dose for cyproterone acetate tablets is 200 mg to 300 mg (4 to 6 tablets) daily, divided into 2 to 3 doses and taken after meals.

For men who have had an orchiectomy (removal of testicles), a lower dose of 100 mg to 200 mg daily in divided doses is recommended. The recommended dose for the long-acting form of cyproterone (Androcur® Depot) is 300 mg in injected into a muscle once a week.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way you are using the medication without consulting your doctor.

Cyproterone Acetate(Ethinylestradiol)can cause weakness and tiredness when you first start to take it. After about the third month, your body will become accustomed to the medication and this effect should be lessened.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Alcohol intake should be limited while taking cyproterone because it may reduce the effectiveness of the medication.

Store the medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

8. What other information should I know before taking Cyproterone Acetate? 

Other medicines, foods and drink

Cancer drugs can interact with some other medicines and herbal products. Tell your doctor or pharmacist about any medicines you are taking. This includes vitamins, herbal supplements and over the counter remedies.

Alcohol

Avoid drinking alcohol while having this treatment because alcohol reduces the effect of the drug.

Treatment for other conditions

Always tell other doctors, nurses, pharmacists or dentists that you’re having this treatment if you need treatment for anything else, including teeth problems.

If you have diabetes

This drug may affect your blood sugar levels if you have diabetes. You need to check your blood sugar more often when you are having this treatment.

Contraception

It is important not to father a child while you are having treatment with this drug and for a few months afterwards. This drug may harm a baby developing in the womb. Talk to your doctor or nurse about effective contraception before starting treatment. 

Fertility

This drug can cause infertility in some men, but it is usually temporary. Fertility can return some months after treatment ends but the time it takes can vary. The effects of long term treatment on fertility is not known.

Talk to your doctor before starting treatment if you think you may want to have a baby in the future.

9. What are Cyproterone Acetate possible side effects?

Tell your doctor as soon as possible if you do not feel well while you are taking cyproterone acetate or if you have any questions or concerns.

Do not be alarmed by the following lists of cyproterone acetate side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.

Infertility and impotence are expected effects of cyproterone acetate and cannot generally be avoided.

Tell your doctor if you notice any of the following.

This list includes the more common side effects. Mostly, these are mild:

-tiredness
-weight changes
-headache
-changes in sex drive
-nausea and gut upset
-unusual secretion of breast milk
-sleep disturbances
-hot flushes
-restlessness

10. Cyproterone Acetate drug interaction 

There may be an interaction between cyproterone and any of the following:

ethinyl estradiol
testosterone and androgens
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, decongestants, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Cyproterone Acetate Ethinylestradiol:Mechanism,Uses,Information

Cyproterone Acetate Ethinylestradiol:Mechanism,Uses,Information Part 1

 

1. What is Cyproterone Acetate Ethinylestradiol?    
2. Cyproterone Acetate Mechanism of Action    
3. Cyproterone Acetate half life    
4. What is the use of Cyproterone Acetate Enthinylestradiol?    
Cyproterone acetate uses- prevent these actions of the androgens:    
Cyproterone Acetate uses-Cyproterone Acetate birth control:    
Cyproterone Acetate uses-Treatment in Women with Acne    
5. Is cyproterone acetate a progesterone?    
6. What forms does Cyproterone Acetate come in?    
7. How should I take Cyproterone Acetate?    
8. What other information should I know before taking Cyproterone
Acetate?    
Other medicines, foods and drink    
Alcohol    
Treatment for other conditions    
If you have diabetes    
Contraception    
Fertility    
9. What are Cyproterone Acetate possible side effects?    
10. Cyproterone Acetate drug interaction    
 

 

1. What is Cyproterone Acetate Ethinylestradiol?

Cyproterone Acetate Ethinylestradiol, CAS No.427-51-0, belongs to a group of medications known as steroidal antiandrogens. It is used to treat advanced prostate cancer.Antiandrogens such as cyproterone block the effect of the hormone called testosterone. This causes a reduction in the production of testosterone in the testicles, which prostate cancer cells require for growth.

Cyproterone acetate may be available under multiple brand names and/or in several different forms. it is sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others. 

Cyproterone is an antiandrogen. It suppresses the actions of testosterone (and its metabolite dihydrotestosterone) on tissues. It acts by blocking androgen receptors which prevents androgens from binding to them and suppresses luteinizing hormone (which in turn reduces testosterone levels).

Cyproterone Acetate Chemical Information

Name	Cyproterone Acetate,Ethinylestradiol
CAS	427-51-0
Molecular Formula	C24H29ClO4
Structure
Molecular Weight	416.94
Melt Point	200-201°C
Storage Temp	2-8°C
Appearance	white powder
Factory	www.aasraw.com
Package	foil bag or customization

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2. Cyproterone Acetate Mechanism of Action

Cyproterone acetate is a hormonal therapy drug used to treat prostate cancer,hormonal therapies affect different people in different ways.What is Cyproterone Acetate mechanism of action? How does Cyproterone Acetate work?

The direct antiandrogenic effect of cyproterone actate is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In addition, cyproterone exerts a negative feed-back on the hypothalamo-pituitary axis, by inhibiting the secretion of luteinizing hormone resulting in diminished production of testicular testosterone.

Cyproterone acetate is metabolized by the CYP3A4 enzyme, forming the active metabolite 15beta-hydroxycyproterone acetate, which retains its antiandrogen activity, but has reduced progestational activity.

3. Cyproterone Acetate half life 

Cypropterone Acetate half life is not long. 

Elimination:

Following oral or intramuscular administration, the plasma half-life is 38 and 96 hours, respectively.

Time to peak concentration:

Peak plasma concentrations are reached three to four hours after oral administration. Following intramuscular administration, mean peak blood concentrations are attained 3.4 days after injection.

Elimination:

Biliary—
        60% in the form of glucuronidized metabolites within 72 hours.

Renal—
        33% mainly in the form of unconjugated metabolites within 72 hours.

4. What is the use of Cyproterone Acetate Enthinylestradiol?

Cyproterone acetate uses is a type of medicine called an anti-androgen. Androgens are male hormones and are produced by women as well as men. They are responsible for stimulating the growth of the skin, including the sebaceous glands that produce oil (sebum), and the hair that grows from the skin. However, if your body produces too much androgen, or if your skin is particularly sensitive to the effects of androgens, the sebaceous glands may produce too much sebum. This can cause the sebaceous glands to become blocked, resulting in infection, inflammation and acne spots. The androgens may also cause excessive growth of the hair on the face and body - a condition known as hirsutism. Both these problems are common in women with polycystic ovary syndrome (PCOS).

Cyproterone acetate uses- prevent these actions of the androgens: 

It works by blocking the receptors in the body that the androgens normally work on. This means that the androgens can no longer affect the skin or the hair and acne and hirsutism can improve. Cyproterone acetate also decreases the production of androgens by the ovaries, so that there are less of these male hormones circulating.

You should notice that your skin becomes less greasy within a few weeks of treatment with this medicine, but it may take a few months of treatment before you see a definite improvement in your acne or excessive hair growth.

Cyproterone Acetate uses-Cyproterone Acetate birth control: 

This medicine is also an effective combined oral contraceptive pill. Cyproterone acetate is a progestogen derivative, and the other ingredient, ethinylestradiol, is a synthetic version of the naturally-occurring female hormone, oestrogen. The medicine works as a contraceptive by preventing the ripening and release of eggs from the ovaries, as well as increasing the thickness of the cervical mucus, which makes it more difficult for sperm to cross from the vagina into the womb. It also changes the lining of the womb so that it is less suitable for any fertilised eggs to successfully implant in.

Cyproterone Acetate is as effective a contraceptive as any other combined pill, but it should not be used solely for this purpose. It is used to treat severe acne and hirsutism in women and has the advantage of also providing contraception(cyproterone acetate birth control). This means you do not need to use any other method of contraception while you are using this medicine(cyproterone acetate birth control), unless you miss a pill, have a stomach upset, or are prescribed certain other medicines as well. See below for more information about all of these scenarios.

Cyproterone Acetate uses-Treatment in Women with Acne

The therapeutic effect of topically applied cyproterone acetate for acne treatment was clearly demonstrated. Topically applied sexual steroids in combination with liposomes are as effective as oral antiandrogen medication in acne treatment, while reducing the risk of adverse effects and avoiding high serum cyproterone acetate concentrations.

HORMONAL approaches to the treatment of acne have been the subject of much interest ever since the sebaceous gland was demonstrated to be sensitive to androgens. The use of topical antiandrogens has had theoretical appeal since the pilosebaceous unit was found to be an androgen-dependent structure. 

5. Is cyproterone acetate a progesterone?

Cyproterone acetate is a 17-hydroxyprogesterone acetate derivative with strong progestagenic properties. Cyproterone acetate acts as an antiandrogen by competing with DHT and testosterone for binding to the androgen receptor. There is also some evidence that cyproterone acetate and ethinyl estradiol in combination can inhibit 5α-reductase activity in skin.Cyproterone acetate is not available in the United States but has been used in other countries. The drug usually is administered daily in cyproterone acetate doses of 50 to 100 mg on days 5 through 15 of the treatment cycle. Because of its slow metabolism, it is administered early in the treatment cycle; when ethinyl estradiol is added, it is usually administered in 50-µg doses on days 5 through 26. This regimen is needed for menstrual control and is usually referred to as the reverse sequential regimen. Cyproterone acetate doses of 50 to 100 mg/day, combined with ethinyl estradiol at 30 to 35 µg/day, is as effective as the combination of spironolactone (100 mg/day) and an oral contraceptive in the treatment of hirsutism. In smaller doses (2 mg), cyproterone acetate has been administered as an oral contraceptive in daily combination with 50 or 35 µg of ethinyl estradiol. This regimen is primarily suited for individuals with a milder form of hyperandrogenism.