weight loss drug sibutramine powder : 四月 2018

Rimonabant became available in UK in the beginning of July 2006 and by 2008, there were 56 countries where it was available. It was meant for people with a BMI greater than 30 or people whose BMI was greater than 27 but who had other risk factors like dyslipidemia and type 2-diabetes.

In June 2006, European Commission approved its sale and it was submitted to FDA for US approval. However, FDA’s EMDAC voted against the drug, concluding that Sanofi-Aventis, the manufacturers of Rimonabant, had not demonstrated its safety effectively. In 2009, EMEA withdrew Acomplia, after suspending it in 2008, because of severe psychological side effects of the drug, such as suicidal tendencies. FDA never approved Rimonabant and therefore, it has never been marketed in the US.

2. Rimonabant

Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. It was rejected for approval for use in the United States. This decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.

3. Brand Name of Rimonabant Variations

Other names for Rimonabant are Zimulti, Acomplia, Monaslim, Bethin, Riobant, Remonabent, Rimoslim and Riomont.

4. Rimonabant powder

Product Name	Rimonabant powder
CAS	168273-06-1
Molecular Formula	C22H21Cl3N4O
Molecular Weight	463.79
Melt Point	230-240ºC
Storage Temp	Refrigerator
Color	White or off white Crystalline powder

5. Mechanism of action-- Rimonabant powder

Rimonabant is a specific CB1 cannabinoid receptor antagonist. There is considerable evidence that the endocannabinoid (endogenous cannabinoid) system plays a significant role in appetitive drive and associated behaviours. It is therefore reasonable to hypothesize that the attenuation of the activity of this system would have therapeutic benefit in treating disorders that might have a component of excess appetitive drive or over-activity of the endocannabinoid system, such as obesity, ethanol and other drug abuse, and a variety of central nervous system and other disorders.

6. How does Rimonabant powder work?

• Rimonabant powder acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle2.

• Rimonabant powder switches off the same brain circuits that make people hungry when they smoke cannabis.

• CB1 receptor blockade with rimonabant powder acts to decrease the overactivity of the endocannabinoid system (EC system).3,4 The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

7. What is Rimonabant powder used for?

• Rimonabant powder was studied to be used complementary to diet and exercise to treat obese or overweight patients who suffer from type 2 diabetes and abnormal levels of fat in the blood.

• Sanofi argued that rimonabant powder could also prevent the risk of cardiovascular disease.

• Patients with large waist circumference (102 cm in men and 88 cm in women) were said to most benefit from taking the drug.

8. Rimonabant for overweight or obesity

Rimonabant is the first drug of a new class of medications that seems to reduce body weight and improve risk factors for diseases of the blood vessels and heart in people who are overweight or obese. We found four studies which evaluated weight loss, occurrence of disorders and adverse effects of treatment. The four studies involved 6625 people comparing rimonabant 20 mg with rimonabant 5 mg and placebo, in combination with a hypocaloric diet after one or two years of treatment. Greater weight loss and improvement in risk factors were seen after 20 mg of rimonabant. These results have to be interpreted with caution though, due to high discontinuation rates of study participants and the overall low quality of the included studies.

We conclude that: average weight loss with rimonabant appears modest and more rigorous studies examining the efficacy and safety of rimonabant are required to fully evaluate the benefit risk ratio of this new drug.

In Europe, rimonabant is contraindicated for patients with severe depression and/or patients who are treated with antidepressive medications. Rimonabant is furthermore not recommended for patients with other untreated psychiatric conditions.

9. Rimonabant powder dosage

Rimonabant powder are taken by mouth. The recommended frequency of using Rimonabant powder is once daily. The maximum single dose of Rimonabant is 20mg.

Rimonabant powder should be taken in the morning before breakfast. Regardless of obesity severity, Rimonabant powder should be taken every day. The maximum recommended duration of using Rimonabant powder is 24 months.

• An adjustment of Rimonabant dosing regimen is not required in elderly patients under 75 years old. Patients over 75 years old should take Rimonabant powder with caution.

• Reduction of Rimonabant daily dose is not required in patients with mild hepatic insufficiency. The reduction of Rimonabant single dose may be required in patients with moderate hepatic insufficiency. Patients with severe hepatic insufficiency should not take Rimonabant powder.

• Change of Rimonabant powder dosage is not required in patients with mild and moderate renal diseases. If severe renal disease is diagnosed in a patient, he should refrain from the use of Rimonabant powder.

• Adolescents under 18 years old were not involved in clinical and post-marketing studies of Rimonabant. Therefore, Rimonabant powder should not be used as a long-term therapy of adolescent obesity.

If you want to buy Rimonabant powder online but have never taken these weight loss tablets, get to know the side effects and potential risks of Rimonabant powder. Before buying Rimonabant powder online no prescription, you can get the information about this weight loss drug by email.

10. Advantages of Rimonabant & the Rimonabant benefits

This supplement has the following benefits:

• It helps obese and overweight people to lose* weight in the safest and easiest way possible. Normally obesity and diabetes go hand in hand and the supplement also helps decrease* the symptoms of diabetes so that the user does not only cut weight but also gets relief from diabetes.

• The supplement can be purchased online meaning that finding it is easier and it also comes with a 30 day money back guarantee. Therefore, if there is a problem with the product or if it does not work for you are assured of getting your money.

• It also comes at an affordable price with small pills that can be easily swallowed. Only pill is recommended daily to achieve weight loss* so you do not have to worry about taking several pills a day and sometimes forgetting some doses.

• The supplement comes packaged well and labeled clearly with all ingredients and their amounts. This enables the user to know exactly that what they are taking is clinically proven and to determine if they have any sensitivity to the ingredients in advance.

• While using Rimonabant you do not need to starve yourself all go through painful and intense workouts. Normal house chores and walks are enough to give you effective results.

11. The warning on Rimonabant

Rimonabant is not recommended in pregnancy and is contraindicated in breast-feeding women.15 The SPC advises “caution” if the drug is used to treat patients with “moderate hepatic impairment”. Rimonabant is not recommended in patients with “severe hepatic impairment” and should not be used in patients with “severe renal impairment”.15 The SPC states that rimonabant should not be started in patients with uncontrolled serious psychiatric illness such as major depression, and that appropriate treament for the psychiatric condition should be started first and rimonabant therapy considered once the condition is controlled. However, it also states that the use of rimonabant in combination with antidepressant medication is not recommended, because of limited data.

12. Side effects of Rimonabant powder

The side effects of Rimonabant powder are so many that they effectively counteract any positive effects that it may present. Even during the trials, it was reported that 1 patient out of every 8 dropped out of the said trials since the side effects became intolerable for them.

The biggest and the most adverse effects, however, were psychological. Depression has come to get associated as a severe side effect of Rimonabant powder. This depression was so serious that it required medical treatment to be managed. Because of Rimonabant powder’s effectiveness against smoking, many people used it for smoking cessation and suffered from suicidal depression.

Many patients experienced and reported extreme anxiety levels after taking Rimonabant powder. Nausea is another side effect which was so severe that it started interfering with the patients’ daily life.

To summarize, the adverse side effects of Rimonabant powder are many –

• Gastrointestinal Problems – One of the noted side effects are diarrhea, dry mouth, loss of appetite, nausea, vomiting and other gastrointestinal disorders.

• Skin Problems – Excessive sweating and itching has been reported.

• Musculoskeletal Problems – Joint sprains, back pain, inflammation and pain in the tendons, and spasms and cramps in muscles are common side effects.

• Central Nervous System – Depression, memory loss, anxiety, mood changes, dizziness, diarrhea and sleep disorder.

While experts speculate that if the dosage is lowered, some side effects may be managed but that still does not change the fact that the drug was never approved in the US because of the severity of its side effects. Also, the side effects that have been reported are rather serious which nullifies the drug’s positive effects against weight gain and smoking cessation.

13. Rimonabant Review

You may be surprised by what I say in this Rimonabant review. We took the time to focus closely on the scientific studies, ingredients, side effects, and customer-service quality. Then we looked at user reviews from all over the internet. At last, we summarized the data we collected to give you the facts.

(1) Safety– “Serious Health Concerns”

Our first issue is the safety of the product. According to our Research Editor, “Post market analysis indicated a higher prevalence of suicidal thoughts and major depressions in patients treated with Rimonabant. The results were concerning enough to have approval revoked in a number of countries.”

One dieter said, “I was in France when this was released and it worked great but I became severely depressed. How can you be that sad and losing weight?” Another claimed, “I was willing to try anything when I was at my heaviest. The side effects were brutal, nothing is worth feeling like that.”

Others did not experience the debilitating depression as a side effect and had a more positive experience. One explained, “It worked great for me and I lost the weight I needed. I didn’t have a problem.” Another said, “I wasn’t as happy as I normally am while I was taking it but it worked so well I would totally use it again.”

(2) Availability– “Not Approved in Most Countries”

It is very difficult to find Rimonabant now because it has been banned in the countries where it was once available. One disappointed dieter said, “I loved it when I used it before but now I can’t find it anywhere!”

Another complained, “I don’t understand why when something works that can’t be enough for everyone. They take away all the useful options.” Some were appreciative of the safety measures. One consumer said, “I liked that it worked so well but it was dangerous. I’m hoping the company tweaks the formula so I can get it again.”

Another claimed, “I still have access to it so it isn’t as big of a deal to me. It isn’t easy but I can get it.” According to our research, safety and availability are two of the major concerns for dieters. If a product isn’t safe, it is difficult to trust that Rimonabant will lead to improved health overall and that ruins your chance of lasting results.

(3) The Science – “Strong Clinical Support?”

At DietSpotlight, we are primarily concerned with how effectively a product works. In the case of Rimonabant, the studies indicated it worked quite well for the majority of dieters. However, the science also shows that a greater number of participants had side effects that could have resulted in their death. This is simply unacceptable.

14. Rimonabant tablet Recipe

Rimonabant tablet is formulated from the following ingredients which are known to support rapid weight loss* in the body safely:

• Rimonabant powder– This is the active ingredient in the supplement and also where it gets its name from. It helps in suppressing the user’s appetite and also increasing* metabolism in the body leading to increased rate of burning fat.

• Meratrim – This is a clinically researched and approved ingredient that helps to lose* fat around the waist where most of the bad fat is contained. It ensures safe weight loss* and also that the user gets back into that attractive figure.

• Chromium Polynicotinate – This is a combination of chromium and niacin and it increases* the absorption of the supplement into the user’s body. This ensures that the supplement works effectively.

15. Does Rimonabant powder also aid smoking cessation?

• Rimonabant powder (Zimulti in the US) was studied by Sanofi-Aventis as an aid to smoking cessation based on studies for up to one year in over 6,500 smokers motivated to quit smoking.

• Sanofi-Aventis submitted a New Drug Application to the FDA, which in turn issued a non-approvable letter for rimonabant powder for use in smoking cessation. In June of 2007, the FDA's Endocrine and Metabolic Drugs Advisory Committee recommended against the approval of rimonabant powder due to concerns over serious side effects such as suicidality.

16. What were the results of Rimonabant powder clinical trial studies?

• In clinical studies, Rimonabant powder was has been shown to improve a wide array of cardiometabolic risk factors as well as promoting sustained weight loss.5,6

• Approximately half of the observed improvement in HDL-cholesterol, triglycerides and HbA1C (an indicator of blood sugar control) in patients who received Rimonabant powder 20mg was beyond that expected from weight loss alone.

• Serious psychological adverse effects, such as suicidality and depression led to the eventual global withdrawal of rimonabant powder by Sanofi-Aventis.

17. Rimonabant for prevention of cardiovascular events

(1) Background

Blockade of the endocannabinoid receptor reduces obesity and improves metabolic abnormalities such as triglycerides, HDL cholesterol, and fasting blood glucose. We assessed whether rimonabant would improve major vascular event-free survival.

(2) Methods

This double-blind, placebo-controlled trial was undertaken in 974 hospitals in 42 countries. 18 695 patients with previously manifest or increased risk of vascular disease were randomly assigned to receive either rimonabant 20 mg (n=9381) or matching placebo (n=9314). Randomisation was stratified by centre, implemented with an independent interactive voice response system, and all study personnel and participants were masked to group assignment. The primary endpoint was the composite of cardiovascular death, myocardial infarction, or stroke, as determined via central adjudication. Analysis was by intention to treat. This study is registered with ClinicalTrials.gov, number NCT00263042.

(3) Findings

At a mean follow-up of 13·8 months (95% CI 13·6–14·0), the trial was prematurely discontinued because of concerns by health regulatory authorities in three countries about suicide in individuals receiving rimonabant. All randomised participants were analysed. At the close of the trial (Nov 6, 2008), the composite primary endpoint of cardiovascular death, myocardial infarction, or stroke occurred in 364 (3·9%) patients assigned to rimonabant and 375 (4·0%) assigned to placebo (hazard ratio 0·97, 95% CI 0·84–1·12, p=0·68). With rimonabant, gastrointestinal (3038 [33%] vs 2084 [22%]), neuropsychiatric (3028 [32%] vs 1989 [21%]), and serious psychiatric side-effects (232 [2·5%] vs 120 [1·3%]) were significantly increased compared with placebo. Four patients in the rimonabant group and one in the placebo group committed suicide.

(4) Interpretation

The premature termination of this trial has important lessons for drug development. A drug that was being marketed for weight loss, but being tested for improving cardiovascular outcomes, induced a level of serious neuropsychiatric effects that was deemed unacceptable by regulatory authorities, and both the drug and the trial were abruptly terminated.

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18. Buy Rimonabant Powder online

(1) Buy Rimonabant Powder Questions & Answers

Q: What are the ingredients in Rimonabant?

A: Rimonabant powder is the major ingredient contained in this drug.

Q: What are the side effects of Rimonabant powder?

A: Rimonabant can induce mental issues such as depression in the users. Furthermore, this drug is also known to induce suicidal tendencies in the user as well as abnormal changes in moods. Other side effects may include itching and excessive sweating.

Q: How do I know if Rimonabant powder is right for me?

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Q: Does Rimonabant powder work?

A: Yes, the drug stood true to its claims and helped its users to reduce their appetite, thereby curbing obesity.

Q: What is the price of Rimonabant powder?

A: The price of Rimonabant is 2600/kg, USD350/100g. The min purity is 98%.

Q: Where can I buy Rimonabant powder?

A: You can order Rimonabant powder online at www.aasraw.com

Q: How should I take Rimonabant powder?

A: Rimonabant powder is available in a low dose of 5mg to a high dose of 20mg. Your need for it and how to administer it must come from the advice of a diet expert. Rimonabant powder is not set out to work alone. It is designed to be used in conjunction with proper diet and exercise to improve a person’s wellbeing while reducing the size of your waistline.

Q: How do I contact Rimonabant customer service?

A: • To contact us by our email inquiry system,or online skypecustomer service representative(CSR).

• To provide us your inquired quantity and address.

• Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).

• Payment done and the goods will be sent out in 12 hours(For order within 10kg).

• Goods received and give comments.

Q: Can I return Rimonabant powder?

A: Yes, Rimonabant powder can be returned according to the return policy of its distributor or supplier.

Q: What are the most common complaints about Rimonabant powder?

A: Some consumers have raised complaints regarding the unsettling side effects of Rimonabant powder.

(2) Rimonabant powder for sale

There are a lot of weight loss products on the market, and Rimonabant powder is one of them, which is loved by many obese people. While Rimonabant powder is prohibited to use in many countries, but because of its powerful control appetite in order to reach the effect reducing weight, still have a large demand in the market, the corresponding Rimonabant powder suppliers will emerge. The well-known supplier is AASraw, the user feedback is very good, and has a great advantage in logistics.

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2018年4月26日星期四

Top 5 Benefits of using Ostarine MK-2866 powder

1.What is Ostarine MK-2866?

Ostarine MK-2866 is a Selective Androgen Receptor Modulator (SARM CAS 1202044-20-9). It was developed by a pharmaceutical company known as GTX to help people to fight against the muscle wasting conditions. It achieves the end result by binding your androgen receptors in the same manner as prohormones or anabolic steroids.

But the benefit of the ostarine is that it will affect only certain tissues, unlike the steroids. Though many of us as men may not have it, deep inside almost each one of us would crave for those strong and shaped muscles and six-pack abs. However, this will remain wishful thinking unless we get up and do something about it. While exercise, good nutrition with the best of proteins are quite vital, there are a few others things too that one must take into account.

There are some selected hormones and receptors which if used intelligently and correctly could help you in proper muscle building and also fat burning. The biggest challenge today with many men is the unwanted but unavoidable deposit of fats. It starts unnoticed and before long it becomes a big menace.

Most fat deposits around the tummy, waist, thighs, arms, shoulders, and chest are stubborn and need special treatments to get rid of them. Amongst the many options available, we will be looking at Ostarine. This is considered to be one of the most potent and effective SARM (Selective Androgen Receptor Modulator). It perhaps has not only helped to chisel and develop high-quality muscles but also has aided in getting rid of those stubborn fat deposits in various parts of the body.

It works by targeting the androgen receptors that are found in the bone and muscles without affecting the other organs of your body. Moreover, it will not be converted into unwanted hormones that you can expect from steroids. It does not offer any severe side effect as well.

2.What is Ostarine MK-2866 powder?

Name:	Ostarine(MK-2866) powder
CAS:	1202044-20-9
Molecular Formula:	C19H10D4F3N3O3
Molecular Weight:	393.35
Melt Point:	70 to 74 °C
Storage Temp:	2-8 °C
Color:	Light yellow crystalline powder

Top 5 Benefits of using Ostarine MK-2866 powder

3.How does Ostarine MK-2866 works?

Ostarine MK-2866 is designed for the increased lean mass gain. While having this supplement, you can expect noticeable lean mass gains. In addition, you will have better strength and you will feel active and dynamic. You will have more endurance. If you have joint pain, you will feel better. This product has joint healing abilities. It will help in weight loss, recomposition, and bulking.

It is designed to bind to the androgen receptor. It shows the bone and muscular selective ability as well. The stimulation and the tying will also intensify the protein synthesis that will contribute to the muscle growth.

The functioning will not be different from the steroids. It will cause the muscle growth similar to the steroids. But the difference is that it will not offer any severe side effects that you find in the anabolic steroids. You can say that ostarine(mk-2866) is safe and offer a natural result without affecting many tissues and other organs of your body.

It uses the anabolic effects on your muscle tissues fully. This ability makes it a good choice to treat the muscle wasting ailments. In addition to curing, it is very effective to build the muscles. It is considered good for the bodybuilders, athletes, and anyone who is interested in the muscle building. It also works as an agent to reduce the degeneration during the recovery process from any serious surgery or any other similar condition. It is scientifically proven.

GTx has done many research and experiments for this product before introducing it into the market. It has conducted a four months IIb trial with 159 patients. All of them have shown a significant difference. They have got a complete boost in total muscle mass in comparison to the other supplements and the methods.

When it comes to the bodybuilding, the users found it very helpful as it helps to improve the lean muscle mass and even the muscle strength. The product is highly appreciated by the users for the muscle building and more endurance.

4.Effects of Ostarine MK-2866

Ostarine MK-2866 can be used for gaining as well as preserving muscle mass. For the athlete, this means it can be used in both cutting and bulking phases. The user can expect significant gains in lean body mass without unwanted water retention or fear of gynecomastia often associated with anabolic steroids. The individual will unlikely gain as much weight as he would from a cycle of Dianabol or Anadrol; however, the gains will be cleaner and easier to maintain post use. It is very common for the individual to associate all weight gain with positive gains when using certain steroids, but lean muscle gains are the only ones that count.

Ostarine MK-2866 can also be very useful during the cutting or dieting phase. This may be the best time to use the SARM CAS 1202044-20-9 for its muscle protecting qualities. In order to lose body fat, you must burn more calories than you consume. Being in a calorie deficit puts lean muscle mass at risk, some loss will occur. If we can protect our muscle mass during a diet, we not only look better we actually continue to burn fat. A loss of muscle mass will hinder the metabolism making fat loss difficult. Protect the muscle mass and you protect the metabolism. Ostarine will also offer up significant joint healing and repair, which is invaluable when dieting. Harsh or hard dieting can often lead to joint discomfort. If we can protect our joints, as well as increase tendon and ligament strength, collagen synthesis and enhance bone mineral content, we can continue to train and train harder. The effects of MK-2866 in this manner are truly beneficial in a bulking or cutting phase, but they will typically stand out more during the cutting phase. The effects of Ostarine in this regard are so strong data has shown it may directly treat injuries, and not a masking scenario as with pain meds but actual healing of joints, ligaments, tendons and bone.

5.Ostarine MK-2866 dosage

MK-2866 is an orally administered SARM CAS 1202044-20-9. For the purposes of muscle preservation when dieting, a minimum of 15mg per day is normally taking. For growth to be spurred, most users will find 20-25mg per day to be a good place to start. Some heavier individuals may find 30mg per day to be needed, but most data shows such doses often make little difference compared to the 20-25mg ranges in most men. Total use will normally last 6-8 weeks with 4 weeks of no SARM use once a cycle of Ostarine is complete. Although testosterone suppression may not be heavy, PCT may or may not be needed. However, some suppression will exist and it’s best to give the body a chance to normalize. MK 2866 carries a half-life of approximately 24 hours; once daily dosing is sufficient. There is no advantage to multiple doses per day.

6.Top 5 Benefits of using Ostarine MK-2866

IT HELPS TO GROW BIGGER MUSCLES

Is increasing muscle mass your main objective? If the answer is yes, you have many reasons to try out quality MK-2866 supplements. They have been proven to be quite effective in increasing lean muscle mass. This has happened not only in athletes and body builders but many cancer patients also have benefited out of it. This is perhaps because Ostarine(mk-2866) is absorbed quickly and efficiently in the body. It has a capability of moving quickly to the various parts of the body.

It is fast acting and you can expect to get highly impressive results within the shortest period of time. There is one more reason as to why MK-2866 supplements are considered so very different from other steroid based muscle building alternatives. It is quite safe and does not come with the negative side effects which are a big problem with many other such steroid based solutions.

IT COULD HELP IN IMPROVING STRENGTH

If you are an athlete or bodybuilder, your success would depend to a great extent on the quality of the muscles and the strength of the same. This product has been found to be ideal for athletes and body builders and also for those who like looking good.

So even if you are fitness buff you have many reasons to try out this product. Apart from helping build muscle mass it also will help the muscles to become strong. Hence, you will be in a much better position to perform well in your respective sporting arena. For non-athletes, it could be helpful in having muscles which not only look good but also have the required strength to do tough jobs.

IT COULD HELP IN HEALING PROCESS

As an athlete, bodybuilder or even as a fitness buff, you have to depend quite extensively on workouts, which at times could be rigid and demanding. Often you could end up with pesky injuries once the training session is over. If you have a competition coming up, or even if you would like to meet your girlfriend, these injuries could be a real botheration. In such situations, you could turn to Ostarine and it has a proven track record as far as speeding up the healing process is concerned. There are studies to prove this.

The impact of SARM in healing injuries is quite impressive according to doctors and fitness experts. It is particularly useful when it comes to handling tendon and bone injuries.

IT COULD IMPROVE ENDURANCE

Yes, all of us would like to have more endurance. Whether it is our day to day activity or performing as an athlete, endurance is a key factor for success. If you wish to reach the best of fitness goals you must seriously consider taking Ostarine(mk-2866) in the right dosage. The recommended dosage is 12.5 mg for four weeks. It has been proven that if you stick to this dosage you will certainly be able to increase your endurance. This in combination with increased muscle mass and improved muscle strength could be a total and complete solution if you are an athlete or even an ordinary fitness buff.

IT COULD HELP IN FIGHTING OSTEOPOROSIS

Because of age and other factors, thousands of us suffer from a condition called osteoporosis. It leads to the bones becoming weak and brittle. This could lead to fractures and other common bone injuries. Such people could benefit if they are put on a controlled dosage of MK-2866. It is known to strengthen the bones quite well and could also help the formation of denser bones. Those who suffer from fractures can also stand to benefit because it could accelerate the healing process quite significantly. This is because of its special healing properties and also muscle building capabilities.

7.How to use Ostarine MK-2866?

Ostarine dosage

For the muscle gain or bulking, the suggested dosage is 25 mg. You will have to take 25 mg on a daily basis for four to six weeks. You will notice the difference in the first week itself. For the best result, you need to be more careful to follow the time period and dosages. If you want, you can also take a high dose of 36mg. You can also continue it for eight weeks. But you will be allowed for this dose and time period if you weigh 210lbs. PCT is not necessary for the normal dose. But if you are taking the high dose, PCT is the must.

What can I use it for?

Like all SARMs used for muscle building, Ostarine is very versatile in what it can be used for. It has shown a lot of potential during the cutting phase. As well as cutting, it has been shown to work great during recomps, helping to gain lean muscle mass, with some added fat loss benefits as well. A bulk is possible on MK-2866, but is recommended to use LGD-4033 instead if you are considering bulking.

For Recomping

Ostarine(mk-2866) works well in recomping due to the nutrient portioning results. A calorie is required to build muscles that will also help in weight loss and will enhance the muscle strength and mass. The suggested dose for the recomping is 13 to 25 mg. You will have to continue it for four to eight weeks. In addition, you need to follow a lean protein diet to get the maximum benefits.

Best sarms for cutting

It also helps cutting while preserving the muscle gains. It will decrease the calories at the same time. The suggested dose is 13 to 5 mg. You can have this supplement for four to six weeks.

For preventing injuries

It is considered good to speed up the injury recovery, especially the tendon and bone-related injuries. The suggested dose is 12.5 mg.

When to take Ostarine?

You can take the suggested doses only once in a day to get the benefits.

Ostarine is completely free from any side effect. You might experience mild natural test shut down while taking the Ostarine. But it will be temporary. Once you stop taking it, you will not have such experience anymore. Ostarine comes with a number of benefits without offering any side effect. If you are looking for a safe and effective supplement for the muscle growth and bodybuilding, you can consider taking Ostarine. It is scientifically proven. Therefore, you can trust the credibility of Ostarine.

8.Side Effects of Ostarine MK-2866

The side effects of Ostarine MK-2866 are limited as it appears to be a relatively side effect friendly drug. Many of the adverse effects associated with anabolic steroids will not exist with this SARM; however, some will, although mildly.

Estrogenic: The side effects of Ostarine should not include those of an estrogenic nature as the SARM CAS 1202044-20-9 does not aromatize. There is no conversion of testosterone to estrogen associated with this drug. Water retention, bloating, gynecomastia or high blood pressure due to water retention cannot occur. However, data shows that some increases in existing estrogen may occur, but should be very mild and not enough to warrant the use of an anti-estrogen. If this very slight increase is concerning, if an anti-estrogen is used, you may easily bottom out your estrogen levels, which can lead to numerous hormone imbalances and related effects.

Androgenic: Androgenic side effects of Ostarine, despite directly affecting the androgen receptor should not exist. This compound does not convert to DHT; acne and hair loss cannot occur. Androgenic side effects associated with virilization in women are also impossible. As there is no direct androgenic activity related to DHT, prostate issues should also be non-existent.

Cardiovascular: The side effects of Ostarine should present minimal cardiovascular risk. Both HDL and LDL levels may be reduced, but all data shows minimal to insignificant reductions.

Testosterone Suppression: It’s often said SARM’s will not suppress natural testosterone production, and it’s true they will not compared to anabolic steroids. However, some suppression is possible, but complete suppression is not. A testosterone-boosting supplement may be warranted while using MK-2866. Post Cycle Therapy (PCT) data is somewhat inconclusive as to if this is needed. Some men seem to experience greater levels of testosterone suppression than others.

Hepatotoxicity: Although orally administered, the side effects of Ostarine do not include liver toxicity. MK-2866 does not belong to the C17-alpha alkylated (C17-aa) class of drugs like many oral anabolic steroids. It does not mirror the MI metabolite associated with the SARM S4 that gives that particular SARM some hepatic activity.

9.Ostarine MK-2866 Reviews

MK-2866 is an effective medication for providing a significant anabolic boost. The personal reviews of many individuals online are mixed with most negative reviews appearing to be based on misunderstanding. This SARM CAS 1202044-20-9 is not going to pack on 30lbs of weight in a matter of weeks like the steroid Anadrol will, and it’s not going to provide a level of hardness comparable to a Trenbolone and Masteron combination. In order to appreciate any medication used for anabolic purposes, we have to first understand what it’s capable of and what it’s not. Ostarine can be a solid alternative over anabolic steroids, a good bridge between steroid cycles (assuming you’re not concerned with full natural hormone recovery at that time), or a good addition to a total stack of other items. You must also consider where you’re getting the product. Most purchases will be made from research chemical companies, and there are some that manufacturer inferior product. However, with numerous high quality labs on the market, most of the poor ones rarely stay in business very long.

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2018年4月25日星期三

Smart drug IDRA-21 powder benefits

1. Smart drug IDRA-21 powder丨What is IDRA-21
2. What is nootropics?
3. How does IDRA-21 work?
4. IDRA-21 research
-Compare to Huperzine A
-Compare to Aniracetam
5. IDRA-21 powder benefits
6. IDRA-21 half life
7. IDRA-21 dosage
8. IDRA-21 side effects
9. Buy IDRA-21 powder

1. Smart drug IDRA-21 powder丨What is IDRA-21

Many so called smart drugs have conventional uses,a popular one Smart drug IDRA-21 powder（CAS 22503-72-6） is a nootropic compund research chemical classed as an ampakine.IDRA-21 powder works as an ampakine stimulant drug and is currently being researched in regards to its effects in memory improvement, cognitive enhancement, stimulation, and reversing cognitive deficits. It’s likely it was developed in 1994 or 1995 as the first clinical trials and peer-reviewed research articles(IDRA-21 examine) appear in the literature in 1995.

Smart drug IDRA-21 powder description
Name	IDRA-21 powder
CAS No.	22503-72-6
Synonyms	IDRA 21;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE;IDRA 21,98%;2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide;AMPAKINE;7-chloro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
Description	IDRA-21 is a benzothiazone derivative. It’s structurally unrelated to Aniracetam, another ampakine drug. It’s a chiral molecule, with the dextrorotary isomer being the active form
Molecular Formula	C8H9ClN2O2S
Molecular Weight	232.69
Melt Point	165-168 °C
Storage Temp	Refrigerator
Color	White powder
Manufacturer	www.aasraw.com
Image	www.aasraw.com

Essentially nootropics will only impact on specific neural pathways which will cause the brain to either speed up or slow down.

Neural pathways are complex and sometimes do not perform exactly as they should, so occasionally the brain and body's reaction may not be exactly as predicted or anticipated. Just like any form of medication or supplement, a nootropic can have different effects and different intensity of effects on different people.

These special classes of compounds can range from herbal teas to synthetically produced powders. Use of Nootropics can help to improve mental focus; promote long-term brain health and in some cases, it has been known that some of the best and more potent nootropics can to help repair damaged neural tissue.

Nootropics, such as Psilocybin (Magic Mushrooms) can have a positive effect on cognitive function, whilst other nootropics such as Caffeine stimulates the brain to the point of being described as a ‘Psychostimulant’. But not all nootropics can have such a far reaching and intense effect.

IDRA-21 powder supplier

2. What is nootropics?

Nootropics are often referred to as 'smart drugs',because they have the ability to enhance cognitive function. They can boost focus, learning capacity, memory, mood, motivation, and energy.

The word 'nootropic' was first used in 1972 by a pharmacologist, who took the name from 2 Greek words 'noos'meaning 'the mind'and 'tropein', meaning towards. The literal translation of the name is ‘to turn towards the mind’.

The drugs have a wide range of benefits and are widely used by people who work in demanding professions and need to keep a competitive edge, and students who are studying for exams.

Modern life is often relentless, so people are turning to nootropics to take them past what they previously considered to be their limits.

3. How does IDRA-21 work?

4. IDRA-21 research

Much of the excitement surrounding IDRA-21 comes from recent animal studies bearing impressive results in the areas of nootropic activity, potency, and lasting of effects.

-Compare to Huperzine A

Huperzine A is a reversible acetylcholinesterase (AChE) inhibitor, its administration results in regionally specific increases in acetylcholine levels in the brain. In human clinical trials, Huperzine A resulted in cognitive improvement in patients with mild to moderate form of Alzheimer's disease (AD) showing its potential as a palliative agent in the treatment of AD.

IDRA 21 powder is a positive allosteric modulator of glutamate AMPA receptors. It increases excitatory synaptic strength by attenuating rapid desensitization of AMPA receptors and may thus have beneficial therapeutic effects to ameliorate memory deficits in patients with cognitive impairments, including AD. The present study evaluated the effects of the two drugs in normal, intact, young adult monkeys to determine whether they can result in cognitive enhancement in a system that is presumably functioning optimally.

Six young pigtail macaques (Macaca nemestrina) were trained on delayed non-matching-to-sample task, a measure of visual recognition memory, up to criterion of 90% correct responses on each of the four delays (10s, 30s, 60s, and 90s). They were then tested on two versions of the task: Task 1 included the four delays intermixed within a session and the monkeys performed it with the accuracy of 90%. Task 2 included, in each of 24 trials, a list of six objects presented in succession. Two objects from the list were then presented for choice paired with novel objects and following two of the four delays intermixed within a session. This task with a higher mnemonic demand yielded an average performance of 64% correct.

Oral administration of huperzine A did not significantly affect the monkeys' performance on either task. However, a significant negative correlation was found between the baseline performance on each delay and the change in performance under huperzine A, suggesting that under conditions in which the subjects were performing poorly (55 – 69%), the drug resulted in improved performance, whereas no improvement was obtained when the baseline was close to 90%. In fact, when the subjects were performing very well, huperzine A tended to reduce the performance accuracy, indicating that in a system that functions optimally, the increased availability of acetylcholine does not improve performance or memory, especially when the animals are close to the maximum performance. In contrast, oral administration of IDRA 21 powder significantly improved performance on Task 2, especially on the longest delay. This finding supports the potential use of this drug in treatment of cognitive and memory disorders.

-Compare to Aniracetam

In a study done with patas monkeys, the experimenters measured the subjects'cognitive performance in a complex behavioral task. The monkeys were given the drug alprazolam before the task was given in order to induce a learning deficit (Thomas et al.) The known nootropic drug aniracetam was pitted against IDRA-21 to test the latter's efficacy in reversing impairment.

Results showed that the IDRA-21 powder was ten times as powerful as the aniracetam in terms of dosage, meaning that the effects were far more potent dose per dose. The effects of IDRA-21 remained persistent for three days after a single dose, marking it as an extremely long-lasting nootropic especially when compared to the roughly 2 to 3 hour windows given by many other ampakines.

Similarly, research done with rats indicates that IDRA-21 powder is useful for reversing cognitive deficit – this time caused by the drug scopolamine.

In both cases, IDRA-21 powder proved effective for treating desensitization of AMPA receptors in the brain, which was simulated by the application of drugs at the beginning of testing. This shows promise for treating people who may have AMPA-related learning disabilities, or enhancing intelligence in those with naturally desensitized AMPA receptors.

IDRA-21 powder benefits

5. IDRA-21 powder benefits

IDRA-21 powder benefits are:

·Clinical trials show that it is an effective nootropic.
·Estimated to be at 10 to 30 times more potent than aniracetam.
·A single dose can last for days.
·It has a good chance of being a mainstream nootropic.

IDRA-21's primary benefit is a dramatic improvement in learning and memory. It significantly outperforms aniracetam and is approximately 10-30x more potent at reversing cognitive deficits caused by scopolamine and alprazolam. Not only that, but this IDRA-21 benefits lasts for up to three days after just one IDRA-21 dosage.

IDRA-21 powder benefits can help to promote a relaxed state very much in the same was as caffeine works as it can either help to kick start the day (morning coffee) or it can help relax (a refreshing cup of tea). Both contain caffeine but in differing amounts.

IDRA-21 powder benefits is also thought to induce long-term potentiation (LTP). LTP is a long-lasting enhancement in how neurons communicate with in the brain. It is vital for improving synaptic plasticity, which strengthens synapses within the brain. As synapses are largely responsible for memories, enhancing their strength and function is vital to improving overall cognition.

The IDRA-21 powder effects will very much depend on personal balance, how much is used(IDRA-21 dosage), and the effects that you are trying to achieve. Nootropics can sometimes be used with other supplements which is a process known as ‘stacking’(IDRA-21 stack) in order to either slow down or speed up brain processing.

6. IDRA-21 half life

IDRA-21 half life is around 48 hours.

7. IDRA-21 dosage

IDRA-21 dosage currently has only had animal trials carried out on IDRA-21 effects. Dosing in a study with monkeys showed that 3 or 5.6 mg/kg body weight was enough to produce cognitive IDRA-21 powder benefits.

Although there are currently no published clinical studies that focus on the IDRA-21 dosage for human consumption, there are several peer-review online sites that suggest positive experiences when IDRA-21 is taken orally. The suggested to promote cognitive function are at 5-25mg.

But this IDRA-21 dosage guidelines need to be given careful consideration, particularly as the IDRA-21 effects can last for up to 48 hours. If a IDRA-21 doses of 5 mg is taken, with no apparent affect then, any additional IDRA-21 doses taken should be with caution given that there may be an overlap of timing that could cause problems.

8. IDRA-21 side effects

Take IDRA-21 is relatively safe, following the classic nootropic definition, IDRA-21 has little to no IDRA-21 side effects. In fact, besides the intended IDRA-21 powder benefits (wakefulness, increased learning ability, etc) it does not do much else.

Anecdotal reports have included slight anxiety and headaches, which could be related to increased glutamate neurotransmission in those who already have strong AMPA activity and don't need IDRA-21.

However, it's best for people who recently had a stroke to avoid this substance, as it could make damage worse according to this research.

9. Buy IDRA-21 powder

IDRA-21 is a chemical that is very difficult to find. Since it's still early on in clinical studies, it may be some time for it to become FDA-approved or even readily available as a 'supplement'of sorts.

However, it is possible to source from some IDRA-21 powder suppliers，the popular nootropic powder supplier(IDRA-21 powder supplier) www.aasraw.com provide high quality IDRA-21 powder worldwide.

Buyers need to make sure that they purchase IDRA-21 from a reputable nootropic powder supplier(IDRA-21 powder supplier) that comes recommended by other customers. Due to the slow neural uptake and the length of time of the effect it may be possible to sell a compound that is either diluted or has no therapeutic value. AASraw company is a reliable nootropic powder supplier(IDRA-21 powder supplier).

2018年4月24日星期二

Buy S4(Andarine) Powder Online| Everything You Want To Know

1. What is S4 (Andarine) Powder?

2. How does SARMS S4(Andarine) Powder work?

3. How To Use Sarm S4(Andarine) Powder and recommand dosage?

4. SARMS Raw Andarine S4 Cycles

5. SARMS Andarine S4 Powder Benefits

6. SARMS S4(Andarine) Side Effects: You Will "GET" What You See

7. What to Consider Before Buying S4(Andarine) Powder?

8. SARMS S4(Andarine) Review: Before and After Results

9. Why lots of people use Andarine(S4) over steroids?

10. Where To Buy Sarms S4(Andarine) Powder?

1. What is S4 (Andarine) Powder?

S4(Andarine) CAS:401900-40-1 is a pale yellow fine powder, the full name of this product is S-40503, but it is commonly known as S-4. it was manufactured by a Chinese pharmaceutical company, AASraw Biochemical Pharmaceutical company. This was originally created to treat osteoporosis. This product is a stronger version of SARM which is more favored by supplement experts. S4 Powder is an orally active partial agonist of the androgen receptor (AR), it is said to be the most potent SARMS which helps sustain lean musclemass while stimulating fat elimination at the same time.In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or antiandrogenic side effects.This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist actions at the AR prevent the side effects associated with the antiandrogens traditionally used for treatment of BPH. Today, Andarine powder is popularly used and sold as a research chemical, which is used by athletes who seek to get all of the strength benefits and lean muscle gains without theharmful side effects observed with anabolic steroids.


Product Name:	Andarine (S-4) powder
CAS No.:	401900-40-1
Molecular Formula:	C17H27Cl2N
Chemical Name:	(2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4- nitro-3-trifluoromethyl-phenyl)-propionamide
Synonyms:	Andarine, Andarin, S-4, S-40503, GTx-007
Molecular Weight:	316.31
Melt Point:	190-200°C
Storage Temp:	Room Temperature
Color:	Pale yellow fine powder
Solubility:	Propylene Glycol, DMSO, Ethanol, PEG400
Physical Form:	Solid
Reports:	COA, HPLC, HNMR

2. How does SARMS S4(Andarine) Powder work?

S4 CAS:401900-40-1 works fittingly with a person’s bone and muscle androgen receptors. Though it doesn’t really help in producing pounds of muscles, it works great in eliminating fats. Bodybuilders who use bulking steroids also take SARMS S4 to erase all those unwanted pounds.

The following have thre type of chemicals that act on the androgen receptor (AR):

1st is the an AR antagonist, which is a chemical that binds to the receptor to prevent it from activating.
2nd is an AR agonist, which binds to the receptor and detaches, then binds again, over and over.
3rd is an AR modulator, or basically a molecule that attaches to an AR and changes its structure to react however it wants.

Each time the AR interacts with testosterone powder, SARMS S-4 powder forces it to produce genes that exclusively benefit muscle and bone growth. In other words, S4 powder is a form of SARM that attaches to the androgen receptor (AR) the same with regular androgens, the only variation is that S4 powder generates selective anabolic activity.As mentioned earlier, SARMS powder function by tying to the AR resulting to anabolic activity. Due to this fastening and stimulation, more protein is produced which allows muscle building. S4 powder can trigger muscle development in the same way as steroids, but minus the same unwanted side effects.S4 is a SARM with utmost androgenic effects and is 33% of the strength of testosterone when attaching to AR. S-4 powder also increases the amount of muscle mass produced by desensitizing the AR to the individual’s natural testosterone to influence a stronger effect.

3. How To Use Sarm S4(Andarine) Powder and recommand dosage?

The typical Sarms S4 dosage is 50-75mg total per day for 4 to 8 weeks, taken in the morning and in the evening in split dosages. If S4 is used with a more anabolic SARM such as Ostarine, the results of recomping will be better if you’re aiming to gain muscles while losing fat. As for the properties of S4 Powder, andarine Powder is often compared to winstrol powder or anavar powder, while S4 powder provides better effects on lean muscle gains. What's more, Andarine Powder also decreases fat while maintaining and even boosting muscle mass in a hypocaloric environment.

Andarine (S-4) 25mg/ml oral liquid recipe:

15g Andarine (S-4) powder
600ml Edible Alcohol

Recommended Dosage: 50 mg for 6-8 weeks.

*Take 2 days off when taking S4 powder(repeat the cycle after the 2 day break) to avoid vision side effects. S4 powder usually is used for 5 days followed by a 2 day break (then this cycle is repeated).

For Cutting

*A 50mg dosing protocol for 6-8 weeks is ideal for cutting purposes for the majority of users.

For Recomping

*S-4 powder cas:401900-40-1 be taken as an orally, it is not methylated and is not liver toxic like other AAS/PH/DS’s. As it prevents this side effect and many others, Recommended intake is 50-75 mg for 4 to 8 weeks, sufficient time to get a good body recomp.

For Bulking

*S-4 powder cas:401900-40-1 isn’t the sarm that comes to mind when we think “BULKING”, but it’s properties in muscle gain shouldn’t be overlooked. Andarine can easily pack on muscle tissue gains with adequate workout and additional calories; however, there will not be any rapid growth which is usually noticed within a bulking cycle while it’s used solo. and jump on some well known bulking SARMs such as LGD 4033 Powder or RAD 140 powder. While there isn’t an enormous 15 lb leap in muscle like these “bulk specific” products, S-4 powder can provide relatively large muscle gains and utilize these excess calories to provide an extra 8-10 lbs in muscle while also keeping the body relatively lean. This steady increase in muscle mass can limit the amount of work one needs to do for a leaner summer body.

For Strengthening

*Andarine powder is great at ramping up power, providing gains that are not only simple to maintain but also extremely clean and fast. When our primary objective happens to be toughness, it is recommended to use a dose of approximately 50 mg, possibly increasing to 75 mg. S4 is well known for its ability to ramp up power, with outcomes beginning to become apparent in only over a week.

S4 Powder cas:401900-40-1 can also be ideal for recomping while stacked with an additional SARM that has a better anabolic impact, for example, Ostarine. For this one should use this drug at 50-75 mg for a period spanning over 4 to 8 weeks.

For optimum recomping, it will be advisable to stack Andarine along with Cardarine and Ostarine for a double stack which is going to provide the best outcomes without any unwanted side effects. Additionally, one should make it a point to consume a diet that has at least 30% of the calories originating from lean protein.

4. SARMS Raw Andarine S4 Cycles

S4 Andarine CAS:401900-40-1 is a well-liked option just before competitions since it is inclined naturally to make a shredded and sculpted appearance. It can be included in an anabolic steroid to enhance a cutting cycle, or a SARMS stack may be produced, incorporating Andarine powder for a powerful weight loss cycle.

S-4 Powder has a half-life of 4 hours, and daily dose recommendation is 50-75mg and tolerable at 100mg, but it’s good to start with a small dosage and increase gradually to minimize possible side effects. You can take it 2-times daily or even 3-times. You can take Andarine optimally for 8-weeks long, it is not hepatotoxic unlike oral steroids and similar drugs, and you don’t have to fear any problem with your liver.

Below table shows sample of Cardarine (GW) and Andarine (S4) Cycle:

Week Andarine (S4) Cardarine (GW)
1 25mgs/ED 20mgs/ED
2 25mgs/ED 20mgs/ED
3 35mgs/ED 20mgs/ED
4 50mgs/ED 20mgs/ED
5 60mgs/ED 20mgs/ED
6 70mgs/ED 20mgs/ED
7 70mgs/ED 20mgs/ED
8 70mgs/ED 20mgs/ED

Using S4(Andarine) CAS:401900-40-1, I recommend 8 weeks cycles at 50mg per day throughout the cycle. and check if your vision side effects are low or something that feels uncomfortable to handle. If it’s fine, keep move up until you hit 70mg, otherwise scale back down to under 50mgs/ED. Don’t extend past this, as you might experience minor shut down.

5. SARMS Andarine S4 Powder Benefits

Andarine S4 Powder CAS:401900-40-1 is for medical use and research only. Researchers have investigated the many benefits of S4 powder as a therapy to improve muscle health and bone density. The research targeted not just the muscle and bone itself, but the overall body pathways that control muscles and bone. Furthermore, apart from its muscle building advantages, S4 won’t cause liver damage, can prevent gynecomastia (enlarged breasts in men) and can help boost your overall health. Reported benefits of selective androgen receptor modules (SARMs) such as S4 (Andarine) powder when used for medical research only are:

Improved lean muscle mass (when treating for muscle wasting disease)
Increased bone density
Preservation of bone mass
Increased strength in men
Improved body composition
Improved spermatogenesis
No side-effects experienced as with anabolic steroids
Targeted treatments for specific needs and muscle-building demands
Very minimal growth on secondary sexual organs such as the prostate.
Testosterone is not diminished in any capacity during the post cycle recovery.
The LDL/ HDL ratio is not affected which makes it a low cardiovascular risk.
Very exclusive in tissue selection and growth which means it will not cause heart enlargement or damage to neighboring organs.
SARMs do NOT require the utilization or devouring of liver enzymes to activate their anabolic effects. This eliminates any risk of hepatotoxicity or hepatitis.
Although SARMs such as S-4 powder cas:401900-40-1 are not as powerful as comparable steroids such as Winstrol powder, they do not require the extensive post cycle therapy and can be cycled back to back throughout the year. Over the course of a year, obtaining the same results is very possible.
SARMs is very female friendly and does not cause excessive masculine features such enlarged sexual characteristics.
0% chance of aromatization, male breast lactation, or rise in any other female characteristic during the post cycle recovery.
S-4 has overall presented larger increases in muscle mass than DHT.

6. SARMS S4(Andarine) Side Effects: You Will "GET" What You See

The biggest concern and most commonly known side effects of S-4 Powder are visual issues, It binds to the ocular receptors in the eye to create a faint yellow tint, which sometimes makes it difficult to adjust to darkness. These side effects are unique to S-4 and are sometimes overblown. If these side effects present themselves, simply stop taking S-4 Powder for two days and stay at a 5 day on/ 2 day off cycle. THESE EFFECTS ARE NOT PERMANENT! Once a ligand (such as a SARM) leaves the system, it’s effects disappear completely.

Lastly, S-4 Powder and most other SARMs have been known to cause depression in a small population of people. This has been discovered as more of a psychological issue than a physiological issue. researchers with mice suffering from any emotional disorders need to be cautious when using this chemical.

S-4 Powder cas:401900-40-1 is a little suppressive at high doses. Comparably, it is not as suppressive as LGD-4033 Powder, but it’s more than Ostarine powder. The recommendation is to follow its use with a post cycle therapy regimen immediately. Even though modified mini-pct is said to be excellent for recovery, using of supplements like HCGenerate is sufficient to address the little suppression caused.

The following protocol is the safest and most effective way of dosing andarine(S4), it will help a user mitigate and hopefully avoid extreme vision effects from occurring.

Week	Andarine (S4)
1	25mgs/ED
2	50mgs/ED
*At this point you must judge the vision sides. If they are minimal, increase dosages by 10mgs; if you're not comfortable, decrease doses back to manageable levels (around 25-50mgs range).
3	60mgs/ED
4	60mgs/ED
*If you feel the sides are alright at 60mgs, you can move up to the magic 70-80mgs range.
5	70mgs/ED
6	70mgs/ED
7	80mgs/ED
8	80mgs/ED
9	80mgs/ED
*At this point, you are probably one of the guys who gets little sides or very manageable sides from andarine. You can move up to the super sweet 100mgs/ED. ONLY if you're comfortable.
10	90mgs/ED
11	100mgs/ED
12	100mgs/ED

7. What to Consider Before Buying S4(Andarine) Powder?

Andarine Powder cas:401900-40-1 , aka Acetamidoxolutamide (try saying that three times fast), can be readily purchased online here.

But before buying it (or any SARM for that matter), you should get a sense of how it works. S4 powder works by attaching to the androgen receptor and binding to it. As it sticks to the receptor, S4 powder interacts with testosterone powder, making it produce genes which enable both bone and muscle growth.

This selective anabolic activity produces additional protein that influences the development of muscle, meaning that it works in a way akin to steroids but without all the adverse effects of the same. Unlike ‘roids, S4 powder doesn’t affect one’s sexual organs or prostate.

For these reasons, it has been carefully studied for its possible potential in treating osteoporosis, age-related muscle degeneration and hypogonadism.

But this is not to say that Andarine powder doesn’t have any side effects of its own. On the contrary, it can lead to some undesirable effects, the most acute of them being vision disturbance. One of the most common side effects of long-term Adarine use (more than 8 weeks), this blurred vision can be accompanied by a slight jaundice of the eyes.

On the plus side, whereas anabolic steroid use leads to male breast enlargement, Andarine powder does not since it does not promote a significant increase in serum estradiol levels.

And that’s hardly where the benefits end. Let’s just say, if your Mini-Me’s aren’t swimming right, Andarine powder has been shown to help.

In fact, S4 Powder got its start as a male contraceptive thanks to its ability to promote spermatogenesis. Not only have studies shown that Andarine can increase male fertility but it can also get your mojo risin’ if you catch my meaning.

Some scientific studies believe that it is essential for the maintenance of male development including muscle mass and body composition. And it’s hard to argue with science.

8. SARMS S4(Andarine) Review: Before and After Results

A lot of S4 users have talked about SARMS S4(Andarine) Before and After Results. There are surprisingly a lot of them. What makes the drug more of a power is how people can get to use it without experiencing troublesome androgenic side effects. So basically, that means that taking S4 powder will not let you experience acne and baldness. Even with excessive body hair growth and women’s virilization, S4 cas:401900-40-1 can never contribute to those.

By using SARMS S4 powder, which is almost the same to Masteron Powder, outstanding results are brilliantly found here. Users of the product have found impressive changes to their bodies by a few weeks of using the drug. They get leaner muscles and their strength and endurance have increased. What lies more here, the drug brings them to enhanced fat oxidation levels and muscle hardness and dryness levels. When it comes to catabolism linked with calorie deficit, S4 Powder works surprisingly with that as well as it sets it off.

9. Why lots of people use Andarine(S4) over steroids?

There are lots of steroid users who actually turned their way out of steroids to shift in taking Andarine(S4) Powder cas:401900-40-1. Andarine offers similar effects to steroids but the drug is way safer than the latter. More than that, other reasons are:

Testosterone is not lowered throughout the recovery.
SARMs do not need the utilization of liver enzymes for activating their anabolic effects. This eliminates any danger of hepatitis or hepatotoxicity.
It offers extremely minimum development when it comes to secondary sexual body organs.
The drug is female friendly. and don’t cause excessive masculine attributes such as enlarged sexual features.
0% possibility of male breast lactation, aromatization, or perhaps rise of any other female feature throughout the post cycle recuperation.
It never causes damage to the heart.
The LDL/ HDL proportion isn’t afflicted which it makes a low cardio threat.
It delivers zero possibility of aromatization and male breast lactation.
S4 Andarine offers bigger enhancements in the muscle tissue as compared to DHT.
Extremely exclusive in the selection plus growth meaning it will never cause heart enhancement or harm to the nearby organs.Although SARMs such as S-4 are not as powerful as similar steroids like Winstrol, they don’t need the intensive post cycle treatment and can be cycled continuously all year round.

10. Where To Buy Sarms S4(Andarine) Powder?

It is quite easy to purchase Sarms Andarine Powder. The internet is known as the fastest and safest way to buy products like S4 cas:401900-40-1. You are provided with different options for your purchase. What’s more is, you’ll be given discounts for every gram you purchase. Even money-back guarantees are offered. But to consider online sellers, you need to be cautious as well. No matter how cheap the price of per gram is, which uniquely delights your eyes, must be well-inspected. For this, you need to know the background of the vendor first before giving your trust.

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